jmichael259:

For AS couples to first or only have AS or AA kids is mere luck. It can even be all sicklers, not just their first child.
Each pregnancy conception has a 1/3(SS,AA,AS) on textbook chance of being SS but in reality actually around 40% chance if parents are both AS.

Remember: This is for each new pregnancy to be conceived. The gene does not start counting during childbirth neither does it know how many kids the couple want.

Your head is very correct.


This means that for each pregnancy, there is 25% chance of having an SS child.

Why would any sane man play Russian Roulette with his wife's womb and claim to love her?


The math is not mathing 🤷🤷

Delight2014:

It doesn't actually work that way my dear
I can attest that some firstborn may be SS, so it varies

he or she didnt pass biology in secondary school obviously

Badhguy:
You can still have up to three kids, all (AS) if you go head. It is from the 4th child that comes out as (SS). You can confirm this by asking your doctor.

Lool. Your biology teacher was definitely a ganja man

Saintmary:




Do you have any idea how risky amniocentesis is?



They will insert a needle into a pregnancy belly from outside to extract something from inside the belly, thereby puncturing the belly, uterus and placenta.


How many Nigerian medical practitioners have successfully performed amniocentesis in Nigeria?


How many hospitals in Nigeria have such facilities to protect the mother and foetus in such a delicate situation?



How many patients are willing to risk precious pregnancies for such a procedure?


All because a man is too lazy to find a suitable bride?

can they do it overseas?


Lastly, in your word, not that the man is lazy sometimes.

izombie:
oboy no be small thing o. Got married last august and i was so worried when we went to do our genotype that same august. Result came out and we were both AA o positive. Na that time i relaxed o.
But my question is, For abroad wey i dey nobody dey talk about genotype o, dem just dey give birth anyhow, dey marry anyhow but i have never seen a sickler here o. Na for only naija this genotype thing dey?

can someone with AS and AS gett married overseas and have no issues?

kay29000:


I wanted to stress this... That cost a lot of money.

12300 USD approx to have it done in Nigeria.

mostHandsome01:
I will be brutally honest with you and summarise as much as I can.

Believe me, it is better to marry who you love and loves you back than to marry someone because they are AA and after marriage, your life becomes miserable. Many ignorant people will tell you, don't marry your fiancee, you will suffer if you do, etc. But the truth is, knowing you and your fiancee are AS doesn't mean you will both go ahead to have children with SS. You can marry your fiancee that is also AS if you are properly informed. Many will tell you it is not worth it. Yes, it is not worth it to give birth to SS children and let them suffer, but it is worth it to get married to who will give you peace and then you both go through other well known, well proven means of giving birth to children without SS.

Some will tell you, it's too expensive to do as though the money is coming out of their pockets. This mostly happens in Nigeria due to the so many uneducated and uninformed people we have . Some are even educated but still uninformed. Technology has changed the scope of many things. To cut the long story short. If you must marry someone who is AS like you. Do not make the mistake of having a child without doing one of the 2 options below...

1) Prenatal testing: fertility clinics in Nigeria do this. When a woman is pregnant, they check the genotype of the fetus, if the featus is AA or AS (75% chance) they leave the fetus. But if the fetus is SS(25% chance) they safely remove the fetus. Now this isn't for everyone as some people may feel it's against their morals to remove a fetus even if it's SS. So for people like this, you can go for the second option

2) PGD : this is a process where a woman's egg is fertilized with a man's sperm. Several specimen will be carried out, the couple can then choose the one with either AA or AS, that way they stand no risk of having an SS child. Some people use this process to choose the gender of a child. And this process can also lead to twin and even more as many celebrities or people looking for children do this and that's why you see them giving birth to twins at once.

Now listen to me, some people will still discourage you. They will say the stress is not worth it because they are already lucky to find a partner that's AA. Some will say the money is too much even though the money isn't coming out from their pocket. The decision is yours and yours alone. If you want to marry for love and peace and the person giving you this is AS. Go for any of the options above. It's all your choice to make. So there you go. You either marry AA, or do any of the options above. Just make sure you do not have SS children.

Correct. Couldn't have said it better. AA+AA/AS can even end having kids with developmental or neurological issues. It's not black and white.

Globalistic:
Follow your heart brotherly.

I am AS and got married to AS. By the special grace of God, our two kids genotype are AA and AS. At the moment, we have stopped raising kids because God blessed us with two healthy boys.

For me, my advise to you is that if your faith isn't large like mine, go for AA.

God will guide and bless your decision.

Did you guys know before getting married that you were both AS?

1Sharon:



I'm from a 1st world country and amniocentesis is not risky at all. The risk is less than 1%.


If amniocentesis is so dangerous in nigeria, let him consider other options.

There is no need to throw his fiancee away without considering all avenues.

can this be done in Australia?

paradigmshift:
can they do it overseas?


Lastly, in your word, not that the man is lazy sometimes.

I have no recollection of such a procedure performed overseas, though I only know of it theoretically.

Now, the purpose of amniocentesis is to test for the genotype of the foetus amongst other tests, possibly in the second trimester, so if it's SS, the pregnancy will be terminated, imagine traveling abroad only to end up terminating the pregnancy, and start over, all the money gone down the drain, spending nearly 4-6 months nursing a pregnancy only to end up aborting it.


So, every pregnancy will send you abroad until you get your desired genotype, is that not foolish?


I maintain that only a lazy person will claim to love only one person stubbornly to refuse putting themselves out there in order to meet someone else.

Prettygirl200:
Nah!!! Why?

Wanna marry you

PrimadonnaO:



12300 USD approx to have it done in Nigeria.

for the pgd or which?

JustANairlander:
Try getting married to an AA that loves you


I JUST LOVE MY GENOTYPE WE NO GET WAHALA AT ALL!

And which genotype do you have?

It's wonderful how AS are always complaining about trivial things.
Meanwhile people living with Sickle Cell are treated like a vile abomination on every level.
Do you know how many jobs I've lost? How many men I've loved and lost? Because of a chronic illness passed down to me from my parents.

Saintmary:



I have no recollection of such a procedure performed overseas, though I only know of it theoretically.

Now, the purpose of amniocentesis is to test for the genotype of the foetus amongst other tests, possibly in the second trimester, so if it's SS, the pregnancy will be terminated, imagine traveling abroad only to end up terminating the pregnancy, and start over, all the money gone down the drain, spending nearly 4-6 months nursing a pregnancy only to end up aborting it.


So, every pregnancy will send you abroad until you get your desired genotype, is that not foolish?


I maintain that only a lazy person will claim to love only one person stubbornly to refuse putting themselves out there in order to meet someone else.

thanks for the explanation. what if both couple live overseas? Have never seen people complain of this sickle cell issues overseas within the African community, is it that they have the facilities overseas to treat it or what? Lastly, you said 4-6 months before checking the foetus, can't it be done like a month or weeks of pregnancy? Lastly, not everyone can double date like you said but life happens.

EmperorFred:
Wanna marry you

Haaaa 😳m still too young for marriage o. M in my early twenties like early twenties. Let me say the beggining of being twenty. So m too young for marriage I might not be able to handle it ni 😟

Angela62:

And which genotype do you have?

My comment says it all

Sorry!!! May the Lord comfort you. 🙏🏾 Amen.

Chee59:
It's wonderful how AS are always complaining about trivial things.
Meanwhile people living with Sickle Cell are treated like a vile abomination on every level.
Do you know how many jobs I've lost? How many men I've loved and lost? Because of a chronic illness passed down to me from my parents.

Prettygirl200:
Haaaa 😳m still too young for marriage o. M in my early twenties like early twenties. Let me say the beggining of being twenty. So m too young for marriage I might not be able to handle it ni 😟

I would love to see your pictures

what tribe sir?

Barbados20:
Goodmorning house. Family and friends are pressuring me to marry but this is the dilemma am going through.

Genotype has become a major barrier for me to get married to lady whom I love. We are tested both AS. My fiancee is from the same ethnic and christian background like me.

On the other hand, I have this female friend whom i recently ask to know about her gnotype. She told me she is AA. Like joke, i ask for confirmation and she brought all d test results frm different lab. The issue is now this female friend is not from my tribe, she from a muslim background although she does not seriously practice it.

My fiancee from my tribal background, but genotype did not match with me. And the other lady from different background, she is AA and match with me. One girl I dated then was AA but the love was not there between us.

Its really frustrating to be AS if you are a Man that want to settle down I am really confused right now. Am above 30. How do i handle this issue of Genotype, ethinc and religious issues? Pls i need advice.

paradigmshift:
how much are we talking about here?

Like ten million naira.

EmperorFred:
I would love to see your pictures

for what kwanu on a faceless forum? Me I said am not ready for marriage na to find who don ready naaaa. There are lots of ladies here that are ready for marriage

Prettygirl200:
for what kwanu on a faceless forum? Me I said am not ready for marriage na to find who don ready naaaa. There are lots of ladies here that are ready for marriage

It's you I want and I'm willing to wait until you're ready

kay29000:


Like ten million naira.

wow that's huge..

Chee59:
It's wonderful how AS are always complaining about trivial things.
Meanwhile people living with Sickle Cell are treated like a vile abomination on every level.
Do you know how many jobs I've lost? How many men I've loved and lost? Because of a chronic illness passed down to me from my parents.

am sorry about that. Your miracle will come in due time .

EmperorFred:
It's you I want and I'm willing to wait until you're ready

lol ewooo u are funny, u don't have to do that? If I want Fi get married 4years later add it to ur age u no go don go far? See it's a matter of starting another relationship like someone said, socialize go to parties, churches, u can still search on social media like Instagram, Facebook and so on u know, u can't wait for me.

paradigmshift:
for the pgd or which?

Yeah. PGD

Now called PGT- M by fertility clinics. Preimplantation Genetic Testing (PGT)

The M means "monogenic."

It's the testing relevant for people with the genotype identification need.

The other one, Chorionic Villi Testing is much more affordable (about 400k for the testing at 10-12 weeks of pregnancy)

The problem however with the chorionic villi Testing is that it predisposes the couple to an evacuation if the foetus turns out to be SS.

There are people who risk it, because the probability of getting an SS is smaller in comparison to the probabilities of getting an AA or AS.

People simply need to know that they have choices.

There's still a lot of ignorance on the genotype issue, unfortunately.

My brother if u mistakenly marry from a different religion, u are finished! Even if the girl is a Christian and she is not serious with her faith na same thing!!!

Badhguy:
You can still have up to three kids, all (AS) if you go head. It is from the 4th child that comes out as (SS). You can confirm this by asking your doctor.

Fallacy.
I have seen many firstborns who were AS.

Barbados20:
Goodmorning house. Family and friends are pressuring me to marry but this is the dilemma am going through.

Genotype has become a major barrier for me to get married to lady whom I love. We are tested both AS. My fiancee is from the same ethnic and christian background like me.

On the other hand, I have this female friend whom i recently ask to know about her gnotype. She told me she is AA. Like joke, i ask for confirmation and she brought all d test results frm different lab. The issue is now this female friend is not from my tribe, she from a muslim background although she does not seriously practice it.

My fiancee from my tribal background, but genotype did not match with me. And the other lady from different background, she is AA and match with me. One girl I dated then was AA but the love was not there between us.

Its really frustrating to be AS if you are a Man that want to settle down I am really confused right now. Am above 30. How do i handle this issue of Genotype, ethinc and religious issues? Pls i need advice.

Please don't take the risk to marry the AS lady. Move on and you will be fine

paradigmshift:
thanks for the explanation. what if both couple live overseas? Have never seen people complain of this sickle cell issues overseas within the African community, is it that they have the facilities overseas to treat it or what? Lastly, you said 4-6 months before checking the foetus, can't it be done like a month or weeks of pregnancy? Lastly, not everyone can double date like you said but life happens.

Try to understand my points.

Don't forget that I'm not a medical personnel, I'm only explaining what I know.



1. Sickle cell cannot be treated, it's for life, most people don't have issues with it because they simply marry someone else to avoid stories.


2. When a pregnancy is in the early stage, it's not easy to insert a needle and find a tiny foetus, so, you'll wait until it's growing bigger. Hence, my estimate of 4-6months.


3. It's not double dating if you end a relationship to start another one, if you're dating more than one person at the same time, then that's what we call double dating.

But, if you already know that your relationship is not going to work, and you're being stubborn claiming to love your partner, that's why I said the person is too lazy to find someone else.

PrimadonnaO:



Yeah. PGD

Now called PGT- M by fertility clinics. Preimplantation Genetic Testing (PGT)

The M means "monogenic."

It's the testing relevant for people with the genotype identification need.

The other one, Chorionic Villi Testing is much more affordable (about 400k for the testing at 10-12 weeks of pregnancy)

The problem however with the chorionic villi Testing is that it predisposes the couple to an evacuation if the foetus turns out to be SS.

There are people who risk it, because the probability of getting an SS is smaller in comparison to the probabilities of getting an AA or AS.

People simply need to know that they have choices.

There's still a lot of ignorance on the genotype issue, unfortunately.

thanks so much I have learned.. with the pgd, I can choose the genotype that I want and even decide to have a twins?

My other questions are ; I haven't seen or heard Nigerians overseas complain of this sickle cell or are there treatment abroad for it or it's not necessary for Nigerians to check for genotype when you are ovseseas ?

Lastly, can this pgd be done overseas?