Over the years, marriages have been conducted without ascertaining the genotype of the intending couples. Hence, many families have given birth to children and they die in their face. Research have shown that most of these children whose genotype is 'SS' dose not live up to two decades. And when they die at such a tender age, the family members tag them an ogbanje(reincarnate) in igbo or abiku(predestined to die) in yoruba, not knowing that it was their ignorance that brought about the death of these children. Also, a research conducted examined defined symptoms of 100 children classified as ogbanje. Haemoglobin analysis showed that 70 of the 100 children had sickle cell disease(SCD) and thereby died in their adolescent age.


What is genotype?

Genotype is the genetic make up of an individual. It(genotype) shows the inherited traits of an individual from his parents. That is why people are able to run paternity test.

Why is genotype a determinant factor in marriage?

There are three possible genotype an individual can possess which are;
- AA normal child
- AS normal but carrier of sickle cell
-SS sickle cell anamiea popularly called sickler.
When a newly wedded couples having both a genotype of AS, when you cross breed it you will find out that there is every 25% chance of giving birth to a child with a genotype of SS.


Effects of giving birth to a child whose genotype is SS.

Sickle cell disease is an inherited disorder in which red blood cells(RBCs) are abnormally shaped. This abnormality can result in painful episodes, serious infections chronic anamiea and damage to body organs. Someone who inherits a sickle cell gene from each parent has haemoglobin SS disease also called sickle cell anamiea. The individual immune system is weak and hence can suffer from tissue and bone damage, strokes and organ failure. The body system is subject to high risk of infections.

These individuals suffers severe sickness from child birth and hence causes pains, worries and anxieties to Their parents. Only minority survive at this tender age, majority die after their parents must have spent so much seeking for a cure.

In conclusion, genotyping(a test carried out to know the genotype make up of an individual) is very essential before marriage. I hereby, advice every couple who wants to wed to go for genotyping before heading on with the marriage plans, in other to avoid the consequences it might bring upon you and your family.

Nevertheless, there are other important test intending couples are expected to run such as ABO blood group, HIV but of these, genotype is very essential.

Since a PhD holder could not add a bit to d betterment of Nigeria, I think we should support a reformed Democrat for the next remaining years than the hates.

PMB is the only hope to salvage Nigeria from its mess.

Vulgar words will strictly not be entertained on this thread.

Ok

Very important

My genotype is AC
can I marry anybody

Nice topic OP, I had the best relationship i could ever think of, and I ad already planned my life around her, sadly i made a mistake not asking the Genotype, tried holding on to the relationship but mehn when people tell you about the plight of SS kids, you just know it's not worth the pain.

Everyone should check their Genotype.

Very important

Op
You forgot to add
Ac and Sc
C too is sickle in nature


The genotype issue is very important.
Taking risk for SS, Sc and As is not worth it. The pain can depress someone's life (parent) ...
There is NOTHING as UNCONDITIONAL love. It doesn't exist. The real love is the "common sense" love.

Highly important

Before starting a serious rship, ask about Genotype. No be say una go do 5yrs and discover yu cant marry because yur genotypes dont match

me no care abeg,,iluv my babe beyond genotyp

Thank God I am AA.

Thanks, so so insightful

Thank God that am AA

Op, you are right but thank God for Molecular Biology and Biotechnology.
All these genes can be mutated if you have the money and qualified hands.

stphil:
me no care abeg,,iluv my babe beyond genotyp

be ready to bury ur children, u may be AS and ur bae As

pcguru1:
Nice topic OP, I had the best relationship i could ever think of, and I ad already planned my life around her, sadly i made a mistake not asking the Genotype, tried holding on to the relationship but mehn when people tell you about the plight of SS kids, you just know it's not worth the pain.

Everyone should check their Genotype.

Awwwwwww. That's actually true. It's very important.

I lost a friend 2 years ago to this genotype ish. It was so sad.

Keep Resting Toyosi.

9ce 1

..... .. Being SS is one thing I do not even wish for my enemy after seeing the travails a close friend goes through on almost daily basis...
... I am AS and I know that getting married to a woman who is AA is non-negotiable...
.... For those who intend to get married and have kids, it's very important that they go for the required tests to avoid birthing a child who will be miserable for most of his/her life.....

Why people always forget AC genotype
We sure do exist.

Hmmmmm....

Very important but often neglected .it's usually considered after d said couple must have fallen deeply inlove

I'm AS and funny enough I fall sick once in 3years, plus my illness may not last up to 2 days cos I'm always all about getting well asap.

ok

mzteemarh:
Why people always forget AC genotype
We sure do exist.

AC as in Air Conditioner? Na joke o


AA we sure do exist too

Op, nice advise.

I believe every Genotype got it's Pros and Cons though. Just that one's cons could be more severe than another.

let me chip this in....

while going for test,make sure you do it in two different hospitals cos atimes they do make mistake.


meanwhile.


please just take a quick look at my signature .
thanks

its extremely important ooooooo



no be joke matter at all

Its amazing dat some pple do not even know their genotype. Smh

A good reminder...love isn't enough

mzteemarh:
Why people always forget AC genotype
We sure do exist.

Madam physicist
I mentioned it too...