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Nairaland Forum / Nairaland / General / Health / Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' (78153 Views)
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Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by AlphaT1(m): 10:19pm On Jul 15, 2017 |
sainty2k3: Pls stop misleading the public with false information, thank you. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by AlphaT1(m): 10:20pm On Jul 15, 2017 |
ChelseaDr: OP is misleading the public with false information and you are supporting it.....why? |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 10:21pm On Jul 15, 2017 |
You just quoted only one study and the study you quoted actually collaborates with what fitnessdoctor said, it doesnt say AA and AS can give birth to SS as you claim. Please stop misinforming people, always show refrences and more than one please. sainty2k3: |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Kam0007: 10:22pm On Jul 15, 2017 |
@OP stop coming to lie here, stop copying and pasting thoughtless and unproven hypothesis from one inane school of thought. you all know nothing and will only confuse yourselves and those that don't know. to simplify this for you and every other layperson, assuming parent 1 is AA and parent 2 is AS, it means that parent 1 will give either of the A's they have in their blood while parent 2 will give either the A or the S part at fertilisation. but these are passed on at random and so it is clearly one thing that you have no control over - parent 1 only has an A part to give while parent 2 cannot decide on whether to give out the A part or the S part - reason again is that they are passe on at random, but the worst that will ever come to them is an AS child. On a lighter note though, it is true that an AA man and an AS woman can have an SS child but of course only if she did cheat with either an AS or an SS man! |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nempi(m): 10:22pm On Jul 15, 2017 |
Thrash! Attention seeking! |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 10:23pm On Jul 15, 2017 |
sainty2k3: op u do not understand the journal at al. besides, the journal there are more information in postgraduate haematology textbook.if you an haematogist or resident in haematology you will know the book. in some, there could be disorder of hemoglobin structure and number which could produce sickle cell and thalassemias respectively. thalassemias is a bad disorder because one or more hemoglobin chains are missing. it is not possible with aa and as to produce ss.pls do not create confusion people. thanks. 2 Likes |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by edeXede: 10:23pm On Jul 15, 2017 |
![]() Op, let me help me simplify it In summary, it is not possible under correct diagnosis for AA and AS to produce SS except AA was misdiagnosed, meaning he is actually AS but was misdiagnosed as AA. Dont come here and be telling us 1+1=1 Na lie. 1+1=2 4 Likes |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 10:23pm On Jul 15, 2017 |
funmisticqueen:Please research more on it rather than discarding a fact Sbeta thalassemia are often misdiagnosed as SS and Abeta thallasemia are often misdiagnosed as AA on electrophoresis, google scholar is your friend, |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 10:23pm On Jul 15, 2017 |
sainty2k3:One of them is not faithful simple and short. Apart from ABO group which has dominant and hiding gene, haemoglobin genenotype doesn't have dominant and hiding gene. Thanks. Pls u can't convince me. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by diva90: 10:24pm On Jul 15, 2017 |
dreshemokha: I agree with you doc. It is IMPOSSIBLE for AA and AS to have an SS child. I'm a nurse and biologist and It is very impossible. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 10:26pm On Jul 15, 2017 |
If you tried, you didnt suceed, even i had a hard time comprehending it, i had to read it twice to get it which was strange for me. sainty2k3: |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 10:27pm On Jul 15, 2017 |
joyandfaith:You didn't read my post and that is obvious unless you do genetic testing or combine other tests like HPLC with HB electrophoresis you might be misdiagnosing beta thalassemia, and yes inheritance of beta thalassemia can co exist with that of sickle cell as S beta thallasemia genotypically which the HB electrophoresis will still show as 'SS' thought its actually Sbeta thalassemia 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 10:27pm On Jul 15, 2017 |
funmisticqueen: op and many here could not understand import of the journal. op is dangerous. hope he is not a doctor sir. if he is mls, I can only pray for people that he would meet. if he is a nurse, no problem, we are still save. if he's not any of above health worker ,ur sin of misinformation is forgiven. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by tosyne2much(m): 10:27pm On Jul 15, 2017 |
oviejnr:So many funny comments on this thread ![]() See as guys dey para for the OP |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by DonMekino(m): 10:28pm On Jul 15, 2017 |
We want instances where AA+AS=SS.....me wey dey think say I have made it in life with my AA genotype.... Chai @op...e no good ooo |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 10:28pm On Jul 15, 2017 |
funmisticqueen:Yea difficult, bit I'm happy I tried, I hope someone with deep knowledge of this will simplify it further |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by stevecantrell: 10:29pm On Jul 15, 2017 |
dreshemokha: Thank u. I wonder what the OP could be smoking. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Opoki(m): 10:30pm On Jul 15, 2017 |
NwaAmaikpe:I will find you and give you a bottle of origin! |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 10:30pm On Jul 15, 2017 |
He cant, he only quoted a news article Scholar212: |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by naijaking1: 10:30pm On Jul 15, 2017 |
sainty2k3: Classic Sickle cell disease denoted by AS and SS are different and must be differentiated from Thalassemia major and minor. Sickle cell: 1. Mostly among African and African American 2. Genetic abnormality is substitution of glutamic acid for valine at the 6th beta position 3. Clinical presentations maybe similar, but doesn't have the variations of Thalassamia Thalassamia: 1. Mostly among people of Mediterranean descent 2. Genetic substitution of glutamic acid for lysine, not valine as in SCD 3. Wide clinic presentations from the instantly fatal absence of both alpha and beta chains of hemoglobin, to mild abnormality of the beta chain at the same 6th position. This understanding is importance for both medical lab technologists who perform these tests, the nurses who counsel the patients, and the physician in charge of diagnosing and managing these conditions. They don't test the same on electrophoresis, because their amino acid components are not similar, therefore if your lab has been identifyoing thalassamia in terms of AS, SS, then that is wrong 3 Likes 1 Share |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by tosyne2much(m): 10:30pm On Jul 15, 2017 |
1StopRudeness:So you go chase am comot? ![]() |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 10:31pm On Jul 15, 2017 |
joyandfaith:I'm a doctor and an authority in the field of knowledge I shared, you find it difficult to understand ,Yes,but those are facts u can verify |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by femi4: 10:32pm On Jul 15, 2017 |
NwaAmaikpe:first time you ll make sense in a long while |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by lexy2014: 10:33pm On Jul 15, 2017 |
nelszx:so u understand all those things they wrote? |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 10:33pm On Jul 15, 2017 |
Nobody with knowledge has actually agrees with your theory sainty2k3: |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 10:34pm On Jul 15, 2017 |
Nobody with knowledge has actually agreed with your theory not to talk of simplifying it sainty2k3: |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 10:35pm On Jul 15, 2017 |
naijaking1:You probably will not get it wrong of you do HPLC with HB electrophoresis or your electrophoresis can also quantify, but if not genotype Sbeta thal . will have an S only band on electrophoresis while A beta thal will have an A only band on electrophoresis which can be misinterpreted as SS and AA respectively |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by S2kluv: 10:35pm On Jul 15, 2017 |
from your link Sickling-negative” people having SS babies; “AA” and “AS” couple producing “SS” babies. Are these possible? The correct answer is “NO!” |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 10:35pm On Jul 15, 2017 |
dreshemokha:being a doctor doesn't mean u know everything pls go and update ur knowledge of hemoglobin defects or simply visit sickle cell center in igbobi Lagos. and yes it is very very possible for a AA and AS couple to give birth to a sickler though not the SS sickler (but electrophoresis will read the genotype as SS) a lot of doctors/ medical personnel don't know this 3 Likes 1 Share |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by AlphaT1(m): 10:36pm On Jul 15, 2017 |
Mods please kindly take down this thread, it is total rubbish, completely false and misleading. It is baseless and unscientific. Medical science is not mathematics, op is probably a mathematician. I think op is just being mischievous. Lalasticlala pls. 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 10:36pm On Jul 15, 2017 |
sainty2k3:ur post, heading and explanation are misleading. see what you posted ' Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' and give birth to SS'. I repeat you are misleading public. accept this and apologize. in haemoglobinopathies, diagnosis is molecular ss is a diagnosis, as is another diagnosis. s beta thal is also diagnosis. if you say misdiagnosis, I can tell u clinically there are subtle difference between s beta thal and ss. that is why input of haematogist is very important to avoid misdiagnosis. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 10:36pm On Jul 15, 2017 |
S2kluv:yes pls go and read about thalessemia u can use google |
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