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Nairaland Forum / Nairaland / General / Health / Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' (78138 Views)
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Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 11:41pm On Jul 15, 2017 |
mayoor15:u are very wrong ma carefully reread contributions here and learn there is nothing new in wot the op is saying and it is a medical fact u can on your own google haemoglobin opting and learn Nigerians like to prodly flaunt their ignorance |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Protein0: 11:44pm On Jul 15, 2017 |
Well, Sainty2k3 ur msg was well deciphered but not the picture you painted really. What u actually meant was that Abeta thalassemia (that a typical Nigerian lab will report as AA) +AS can yield Sbeta thalassemia (that a typical Nigerian lab will report as SS). This is a fact! However, d only way a couple with "real" Hb AA and AS (not Nigerian's) can produce a child of Hb SS is if a "third party" is involved. ![]() A doctor can't say if a supposed genotype result has thalassemic copy, even if he's sure it was based on electrophoresis alone. Kindly call on d mods to modify d topic to avoid that break up of these love birds out there. ![]() 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 11:45pm On Jul 15, 2017 |
jnrremedy: I know. I still maintain that op is misleading. no haematogist will label a child SS when parents are AA and AS. more questions need to be asked. that is standard practice. in above case, genetic testing or chromatography could solve the problem.medical diagnosis does not stop in bench. besides, we disagree with op heading. there is discordant between heading and explanation given by op. even explanation is shallow and not appropriate for non-health workers. you are asked me to read about thal? you must be kidding or joking. if you want info on thal even molecular pathogrnesis, newer diagnostic methods, pls open another thread. you guys know few things and start spitting meconium. he should change the heading to " MEDICAL LABORATORIES IN NIGERIA CAN MISDIAGNOSE AA or AS as SS''. it would make sense. 7 Likes 1 Share |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 11:47pm On Jul 15, 2017 |
edeXede:Your exception was close tonit meaning he is actually Abeta thal but electrophoresis diagnosed as AA |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 11:50pm On Jul 15, 2017 |
jnrremedy: ![]() ![]() ![]() It is important we disseminate info with valid facts especially on sensitive topics like this. Hb electrophoresis remains the conventional diagnostic investigation for genotyping all over the world. There are other advanced techniques like PCR and Isoelectric focusing for confirm genotypes but these investigations are very expensive & most hospitals including tertiary health facilities don't have them. The thalassamias are known to rarely occur in the black population. The prevalence is very low. I accepted the OP to tell us, what Thalassamias are, how they are inherited, diagnosis, clinical presentation of patients, laboratory findings in such patients etc. And not confuse the public by telling us it is possible for AA + AS = SS. That is a fallacy & a scientific blunder! 5 Likes |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 11:51pm On Jul 15, 2017 |
Protein0: you are 100% right here but it's only those in the field that will get the full gist. a lay man interpret all sicckler as having Hb SS reason op interchanged SS with Beta major For an ordinary couple having any child heamogblobinopathy is translated to HbSS so its better to explain to them on that level. with even comments here u can see most people don't know being a sickler is more than HbSS. and also most medical labs will interpret all haemogblobinopathy as HbSS cos of the diagnostic tool they ate using |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 11:51pm On Jul 15, 2017 |
jnrremedy: thread should be closed or op should change the topic to " MEDICAL LABORATORIES IN NIGERIA CAN MISDIAGNOSE AA OR AS GENOTYPE AS SS''. this public forum , most people here could relate to simplified health information. 3 Likes |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 11:51pm On Jul 15, 2017 |
funmisticqueen:How many people of knowledge in the field of haematology do u know and if you know any have you tried to ask them |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 11:52pm On Jul 15, 2017 |
jnrremedy:wow......what a journey of realization,i read through every post to understand this. 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 11:57pm On Jul 15, 2017 |
being low doesn't mean they don't exist I have seen a personal case of misdiagnosis by the same medical personnel cos of their poor knowledge of heamogbobinopahty this is just like an awareness to sensitive the populace even here on Nairaland some years back ( 3 yrs) someone brought up a personal case and everybody Ill advice the person involved ( including me cos then I was not informed) they concluded the wife cheated cos the hospital/ lab result keep coming as HbSS while parents are Hb AA/AS |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 11:58pm On Jul 15, 2017 |
joyandfaith: ![]() ![]() ![]() Your suggested topic to the OP is very unattractive & troublesome. You are throwing punches at the medical laboratory profession without any cause or evidence that they have misdiagnosed someone. E b lyk say u like fight ba? He can try; Diagnosing the thalassamias, common limitations in Nigeria. 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 11:58pm On Jul 15, 2017 |
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Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 11:59pm On Jul 15, 2017 |
sainty2k3:Quite educative though, but based on your write up.... the child is not actually SS but SB,but everybody took it as SS.Educative though. 2 Likes |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 12:00am On Jul 16, 2017 |
Scholar212: https://www.stjude.org/treatment/disease/sickle-cell-disease/diagnosing-sickle-cell/beta-thalassemia-trait.html |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 12:01am On Jul 16, 2017 |
SAVEDBABA:You are right |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 12:02am On Jul 16, 2017 |
donhils: https://www.stjude.org/treatment/disease/sickle-cell-disease/diagnosing-sickle-cell/beta-thalassemia-trait.html |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 12:03am On Jul 16, 2017 |
jnrremedy: Tell Dr Abiessuku of Chemical pathology you have poor knowledge of hemoglobininopathies. Tell Dr Osho P.O that you were sleeping in class during lectures. Partial knowledge is your problem. Pls, do not say AA and AS can produce SS in any conference. if you do, u get know in ur head. so, if chromatographymedical or pcr is used, AA and AS will still produce SS. nonsense. 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by oluezekiel(m): 12:04am On Jul 16, 2017 |
SAVEDBABA:Summary of the whole argument I believe. I don't know why people are abusing the op instead analysing it logically. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 12:04am On Jul 16, 2017 |
innosaint27: better. but it will not hit front page. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 12:05am On Jul 16, 2017 |
sainty2k3:You need to change your topic then.*cheers* 1 Like |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 12:05am On Jul 16, 2017 |
CanadianNurse:But my title didn't say Genotype, I'm referring to phenotypes AA and AS which most people wrongly refer to as genotype |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 12:07am On Jul 16, 2017 |
oluezekiel: because op thinks he is talking to health workers or medical researchers. many people here cannot analyze it logically. we could have helped him to analyze if topic is changed. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 12:07am On Jul 16, 2017 |
AmbFitsaint:Engage any consultant hematologist with this write up ,they will explain it to you, probably better |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by chineduemmao: 12:09am On Jul 16, 2017 |
NwaAmaikpe:nwaAmikpe and his always-controversial comments SMH... |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 12:10am On Jul 16, 2017 |
joyandfaith:OK o get it u are probably an hematologist so u understood all along but the doctor in u want to prove u know it all............. if u are practising in Nigeria u know most doctors ( general practitioners ) will only stop at the gel electrophoresis level. you know cos u are an hematologist so don't think others no. I have come across a lot of doctors ( even non hematologist consultants) that will tell u they don't know its possible and will never ask for a confirmatory test if faced with same case |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by sainty2k3(m): 12:11am On Jul 16, 2017 |
joyandfaith:You can still give your analysis let's here or open another thread and explain better ,I will be happy to see that from you. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by dmcdad: 12:13am On Jul 16, 2017 |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by joyandfaith: 12:13am On Jul 16, 2017 |
sainty2k3:no haematogist will say AA and AS will produce SS. heamatologist can talk about misdiagnosis which can be resolved by use of pcr or chromatograpy methods. I be not seen haematogist spitting this kind of meconium. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 12:13am On Jul 16, 2017 |
jnrremedy: ![]() ![]() ![]() There are many discrepancies these days with Lab results due to quackery, but that is being checked by the relevant body concerned. There are many individuals who assume their genotype and blood group. You ask them & they tell u " i am genotype AA and blood group O+" without ever going for the test. There are others who go for the test but end up in the hands a quacks. It is highly recommended that such tests be done in Teaching Hospitals or General Hospitals. Not private facilities pls. A father and mother who both claims to be AA but produces an offspring who is AS or SS will have lots of questions to ask. But, before they do, let them be honest with themselves and go for the test in a recommended facility. If they have done so before, let them have it repeated in that facility and elsewhere again. MUST BE A GOVT HOSPITAL. Likewise that of their offspring. At the end of the day, the discrepancy will be uncovered. Most times, you will discover that either of the parents had never been tested or was tested but in a quack facility where wrong result was issued. |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by oluezekiel(m): 12:14am On Jul 16, 2017 |
SAVEDBABA:You summarized it very well and rightly 'closed' the thread. If you're not in the medical field, your IQ is perfect. Well done 2 Likes |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by Nobody: 12:15am On Jul 16, 2017 |
joyandfaith: Getting it right is more important than a misleading caption to get FP. How much them go pay am to hit FP?? Lol |
Re: Yes, It Is Not Impossible. 'AA' Can Marry 'AS' And Give Birth To 'SS' by jnrremedy(m): 12:16am On Jul 16, 2017 |
joyandfaith:I never said anywhere that AS and SS will produce SS u now that pls read all my post and point to where I said that. that is one thing I don't like about doctors ( i have a lot of them as freinds) they believe they know it all that nobody can know more than them |
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