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Nairaland Forum / Nairaland / General / Family / Undetected Sickle Celler (73040 Views)
Parents With Sickle Cell Kids How Do You Cope? / Nigerian Man Marries With ‘fake’ Genotype, Abandons Wife With ‘sickle Cell’ Kids / Advice Concerning : Undetected Sickle Celler (2) (3) (4)
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Re: Undetected Sickle Celler by toprealman: 9:21pm On Jan 30, 2021 |
pragmatistm:Stop defending what you don't know. If you adopt a baby today, it is not very unlikely that the baby will resemble you at some point later in life. We do annual check and I remember the Lab guys getting my genotype wrong. Some others people where also affected. The possible causes: 1. Gene mutation: exposure to various mutagens could have caused this. Very slim though. 2. Wrong diagnosis: most lab in Nigeria should be closed down. From useless equipment that consistently malfunctions to incompetent personnel handling these good for nothing equipment. 3. Baby mixed up at birth: Forget Nollywood, this shii actually happens. 4. Away game: In this era of DNA test, yes the hubby is AS, the possibility of being bunked outside should also be explored. These things have a way of catching up with both the doer and the doee ![]() 3 Likes 2 Shares |
Re: Undetected Sickle Celler by zikter(m): 9:22pm On Jan 30, 2021 |
BRATISLAVA:Do not move from the point, you kept insinuating the man's genotype was hidden so as to blame the woman, while it was clearly mentioned in the story which you didn't read but pre planned to blame the man. It is no a question of if the story is true or not. It is a question of not reading before commenting, which is a great disservice to people following comments here. Assuming your theory of ss from the man is true, how come AA and SS birthed SS? If you wanted to question the validity of the story, you should have done that straight away. But, no you went straight to the man's jugular when he had not done anything wrong. 5 Likes |
Re: Undetected Sickle Celler by Vaiki(m): 9:22pm On Jan 30, 2021 |
Winneygirl:smart girl! 1 Like |
Re: Undetected Sickle Celler by Ajixegun: 9:23pm On Jan 30, 2021 |
osazsky: Is just poor kid they brought into this excruciating country with excruciating condition that I'm feeling for. |
Re: Undetected Sickle Celler by thundafire: 9:24pm On Jan 30, 2021 |
zikter:oh |
Re: Undetected Sickle Celler by toprealman: 9:24pm On Jan 30, 2021 |
OP you seem to be the person involved because you know a bit too much here about this "person". 3 Likes |
Re: Undetected Sickle Celler by osazsky(m): 9:24pm On Jan 30, 2021 |
ikabasa1:true talk sir ..u are wise..one cold beer for you.the average nigerian woman is desperate..look at op talking of integrity as if she is her sibling..make them pet am she go confess..7 times ..na scan |
Re: Undetected Sickle Celler by sircatherine45(m): 9:26pm On Jan 30, 2021 |
Caaz:Likely scenario |
Re: Undetected Sickle Celler by ejihand(m): 9:26pm On Jan 30, 2021 |
pragmatistm: Stop lying wilfully. AS variants has no special "tedious" procedure. It same procedure. Infact , it's appearance is very clear and distinguishable from other genotype variants. I am a seasoned laboratory scientist. Supposing the SS variants was mistakenly for AA variants, that could be forgivable. But for AS. No no no abeg. She is hiding something. The woman is a liar. Op could be the culprit here. 5 Likes |
Re: Undetected Sickle Celler by frog12: 9:26pm On Jan 30, 2021 |
what kind article be this? it already said the woman came back as AS. so that explains why the child is SS. the previous lab tests she did was fake results. frog12: |
Re: Undetected Sickle Celler by AbujaCitiBlog: 9:26pm On Jan 30, 2021 |
pragmatistm:She is an evil woman! She wanted to marry the man at all costs! That's how they behave. Desperados! She has been manufacturing results in connivance with some lab scientists for a few thousands. Most women of nowadays are scum! Do not accept HIV test or gentotype test from her own lab or her own Doctor! Evil women everywhere! These vagina people are terrible! 2 Likes |
Re: Undetected Sickle Celler by AbujaCitiBlog: 9:26pm On Jan 30, 2021 |
pragmatistm:She is an evil woman! She wanted to marry the man at all costs! That's how they behave. Desperados! She has been manufacturing results in connivance with some lab scientists for a few thousands. Most women of nowadays are scum! Do not accept HIV test or gentotype test from her own lab or her own Doctor! Evil women everywhere! These vagina peopleare terrible! 1 Like |
Re: Undetected Sickle Celler by Dalby(m): 9:27pm On Jan 30, 2021 |
pragmatistm: First of all it is odd that you will do 7 test for genotype especially when the first one tells you that your genotype is AA. She has been AS all along and probably doctored the genotype results all along... ![]() ![]() ![]() 2 Likes |
Re: Undetected Sickle Celler by tuzle(m): 9:27pm On Jan 30, 2021 |
thundafire:guy read again, it was said that she later did a test after the child was confirmed to be SS and it came back as AS |
Re: Undetected Sickle Celler by nextstep(m): 9:27pm On Jan 30, 2021 |
It just means we have lousy testing in this country. ![]() |
Re: Undetected Sickle Celler by osazsky(m): 9:27pm On Jan 30, 2021 |
Ajixegun:my bro last month here a girl offered my wife 50k..to change her negative pregnancy test result to positive just to put it on an inocent guys head..these people are stupid o..i will continue to support dna testing in nigeria no matter how expensive these bitchess are heartless o and self centered |
Re: Undetected Sickle Celler by Vetzy12(f): 9:28pm On Jan 30, 2021 |
I work in a medical laboratory.. We usually run our genotype twice before giving out the result.. Sometimes we advise couples to do a repeat test elsewhere for confirmation if they are still in doubt. You can't tell me 7 different lab confirm she was AA and now she is AS.. I suspect a foul play.. Why did she go to 7 Lab in the first play is she wasn't AS. 4 Likes |
Re: Undetected Sickle Celler by abimic(m): 9:29pm On Jan 30, 2021 |
JovialJune:How many times have you confirmed yours? ![]() ![]() ![]() ![]() ![]() ![]() |
Re: Undetected Sickle Celler by FanOfMyself: 9:30pm On Jan 30, 2021 |
JovialJune:I think he meant that AA genotype are prone to malaria than AS and SS. I'm AA and I easily get down with malaria anytime I am exposed to mosquito bites, a friend who is AA confirmed same few days ago when we I was taking malaria drugs. Aside from malaria, I have never suffered from any sickness as far as I can remember |
Re: Undetected Sickle Celler by studentofTruth: 9:30pm On Jan 30, 2021 |
pragmatistm: It is possible the woman is AA but also most likely a beta thalassemia carrier, which most Nigerian labs don't test for! The child inherited a HbS gene from the father and a beta thalassemia gene from the mother. Here's what is likely going on in the child: The thalassemic Hb gene from the mother cannot produce any reasonable hemoglobin. The HbS gene from the father produces sickled hemoglobin. The end result is the child having sickled hemoglobin in his/her blood, which Nigerian labs would tag SS. But, genetically, the child is HbAS with an inactive (beta thalassemic) HbA component and an active HbS component! Some of you are wondering why she did test 5x and 2x again during antenatal: Well, someone may have had a hemoglobinopathy (beta thalassemia) in her family, which she, just like any of you here, might have thought was sickle cell anemia. So, she wanted to be sure she doesn't have it. Obviously, she doesn't have the beta thalassemia, but unfortunately, she's a carrier. The point is, SCD is not the only hemoglobinopathy; there are others like beta thalassemia, which are also recessive. When a carrier of SCD (AS) marries an AA who's a beta thalassemia carrier, they can have an AS child that manifests as SS because the HbA component is inactive! Regarding the woman's latest test that showed AS: The result cannot be trusted! The principle of "when you know what you are looking for, that's what you will find" was most likely at play there. It's a very important principle in medicine, which is why in clinical trials to ascertain the effectiveness of a drug, researchers do a double blind randomized study — both the doctor and the patients don't know who's receiving the real drug and who's receiving the placebo so as to remove the effects of biases. My point is, the lab scientist who did the last test (which was after the child tested positive for sickled hemoglobin) was already biased. S/he knew what they're looking for and that's what s/he gave as the result. I would rather trust the previous 7 tests than trust that last test. To clear the doubt, a new test (possibly HB electrophoresis) must be done by a new lab without prior knowledge of the situation! This being on this page, I'm concerned that most people won't see it. @Ishilove, you can create a thread with the information here and put it on the front page so that people can learn and stop castigating the woman. She's lucky that she wasn't the AS and her husband AA; if not, she would have been accused of paternity fraud while innocent! 3 Likes |
Re: Undetected Sickle Celler by osato45: 9:30pm On Jan 30, 2021 |
Cooked up story to gather traffic, if you know, you know |
Re: Undetected Sickle Celler by JovialJune(f): 9:32pm On Jan 30, 2021 |
Re: Undetected Sickle Celler by Srallens(m): 9:32pm On Jan 30, 2021 |
BRATISLAVA:. Did you even mind reading the post before your comment, oh thou BRATISLAVA? |
Re: Undetected Sickle Celler by AdeolaOmoOba(m): 9:33pm On Jan 30, 2021 |
People please don't bother thinking along the line of DNA test o. |
Re: Undetected Sickle Celler by JovialJune(f): 9:33pm On Jan 30, 2021 |
FanOfMyself: Well I don't get sick of even malaria, not all AAs get sick of malaria easily. 1 Like |
Re: Undetected Sickle Celler by etrouble: 9:35pm On Jan 30, 2021 |
NoToPile: I am AA snd I have NIN, can you try that? I married SS. I did not do any genotype because I have always known myself to be AA. It was the Church that did medical test for us and reconfirmed that I am AA and my wife SS. So, why was the woman going all over the country doing genotype everywhere? Something is hidden 1 Like |
Re: Undetected Sickle Celler by FanOfMyself: 9:35pm On Jan 30, 2021 |
JovialJune:Ok dear, just read this https://www.google.com/url?sa=t&source=web&rct=j&url=https://scialert.net/fulltext/amp.php%3Fdoi%3Dpjbs.2006.452.456&ved=2ahUKEwj0wsSgvsTuAhWrx4UKHWjACdgQFjABegQIAhAF&usg=AOvVaw1vdg_OG-L4Vzf2zKZB7F9Y&cf=1
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Re: Undetected Sickle Celler by abimic(m): 9:35pm On Jan 30, 2021 |
How jobless could one be to b confirming genotype 7times? that even gave her off to be hiding something. I did mine in two separate big hospitals, to be very sure, so why running them 7 times, and getting same result, i would not even blame the labs, but the woman, she must have lied to herself one way or the other, 7 good different labs can never be wrong except she bought the results with money. She has been AS all along which she knows, she just was deceiving herself. 2 Likes |
Re: Undetected Sickle Celler by Ajixegun: 9:35pm On Jan 30, 2021 |
osazsky:Ah! All is well. |
Re: Undetected Sickle Celler by iPopAlomo(m): 9:35pm On Jan 30, 2021 |
pragmatistm: Nothing to see here... Do DNA test Next!!! |
Re: Undetected Sickle Celler by osazsky(m): 9:36pm On Jan 30, 2021 |
If she wasnt AS why run the test 7 times. She dey hide something.whoever believes this woman can believe anything like tomorrow beign april 5th 1978 nonsence .poor child..the woman they find who she go blame so that people will not insult her..excuses are lies we tell ourselves so that it doesnt have to be our fault |
Re: Undetected Sickle Celler by Melonny(m): 9:36pm On Jan 30, 2021 |
Ishilove:You are right. I have done the test 4 times at different stages in my life and the result didn't change for once. She is a liar |
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