Verysmart101:

.u said two labs were wrong but was the third trial wrong too?

Toneyo:
Same thing happened to me. Prior to marriage. My wife claimed she was AA. I'm AS. I demanded for test result. She told me she can't find it again as it has been very long she did the test.

She claimed all her siblings are all AA. The whole thing bursted when my 3rd son fell seriously ill. He always for sick until a day, he had priapism at such young age, so I took him to the hospital.

I demanded the lab technician to conduct a genotype test and blood group test. He turned out to be SS, but same blood group with mine.

Wife was still claiming she was AA. Right there, I demanded she took a genotype test. Within minutes result was out. She is AS. She scammed me. Ever since that time my marriage has been a shamble.

She never apologized for the lie. No remorse till this day. I have been doing everything not to lose that boy.

So, many things has really happened from that day. Lots of discoveries. I was never truly loved but for the sake of I want to get married. All for her selfishness.

Winneygirl:


1,2,3, maybe 4 times might be considered being cautious.
But 5,6,7 times seems out of place to me.
We don't know her family history. We don't know if she has a sickle cell sibling.

Something made her jittery enough to keep running the test even after marriage.
That is the missing piece of information.

BRATISLAVA:


Didn't see that. Oh well, they should know they both contributed to it. Both parents gave the gene. Both are responsible. Even the man could actually be SS.

mariahAngel:


Munz.y14, you need to read this post.

Remember when we talked about genotypes, bonds and letting go?

dalongjnr:
Mistakes too many happened.
1. She maybe have lied about her genotype or pay her way to have a fake result in other to consummate the marriage.
2. Expired reagents or poor rocking of the plate may be responsible. But on 7 occasions, I doubt.
3.The child probably may have been swabbed during delivery but very rear.
4.Possible, but unlikely!
There's a very slim chance that a new mutation can occur in an egg or sperm cell - or in a very early stage embryo - that changes a specific genotype like this. The mutation wouldn't be present in the mother or father, but it would be present in a child that's conceived using the mutated egg or sperm cell, or in any embryo where the mutation occurs after conception. This is called a de novo mutation. It's hard to pin down the overall rate of de novo mutation, but we do know that it's more likely to occur when the parents are older at the time of the child's conception.
One other possibility is that one of the parents is a genetic mosaic. This can happen when a
de novo mutation occurs after a fertilized egg has already divided at least once; the person will have the mutation in some, but not all, of the cells of their body. It can also occur when two non-identical twins fuse together very early in development. If one of the parents is a mosaic, and their egg/sperm cells are produced by a genetically different part of their body to their blood cells (or whichever other cells were sampled to assess the parents' genotypes), then you might see this AA/AA/AS phenomenon. Apparently this is more common than was previously thought!

Ishilove:

And all the 7 tests confirmed she was AA prior to the child's diagnosis, but after diagnosis the result turns to AS? How very convenient

Winneygirl:
As she is not the one making the post, there must be something we don't know yet.

Most people don't do genotype testing 7 times.
If you're AA, you do maybe one confirmatory test before marriage, that's all.

Why was she running up and down doing genotype test?
It is because she knew she was AS long ago.

pragmatistm:


I tell you, she is a very upright person but the fault is with the inexperienced personnels in the various labs.

I need the medical persons to come and say something on this matter. I have just learned that to detect certain AS genotype used to be problematic in the laboratories. Please medical people, over to you.

shugabasbn:



Do u read the aspect that the doctor asked her for repeat her genotype which turned out to be AS.

pragmatistm:
You need to hear from laboratory practitioners before you jump into conclusions and castigate an innocent person OK. My wife is a laboratory practitioner and informed me how tedious it used to be with certain AS blood sample and how it always show as AA.

Besides, I reported that even twice during antenatal in a government hospital, her results came as AA. So is it her fault?

pragmatistm:


I tell you, she is a very upright person but the fault is with the inexperienced personnels in the various labs.

I need the medical persons to come and say something on this matter. I have just learned that to detect certain AS genotype used to be problematic in the laboratories. Please medical people, over to you.

pragmatistm:
Good day family people. Please what can you do in this case?

My neighbour's second child, 5 year old girl that used to fall sick often was just recently confirmed sickle celler much to the surprise of the parents and all of us. But that is not even the issue.

The real issue is that the parents tested to know their genotype before marriage and the father was known to be AS and the mother AA. The woman went to 5 different hospitals and laboratories, government and private, to confim her genotype before committing to marriage with the man. After their marriage and during her two antenatal in the hospital, she tested her blood each time again and her genotype was still confirmed AA. Now suddenly when her daughter was fallen sick often she requested for genotype test for the daughter and it was confirmed she was SS. That made the doctor to ask the mother to go for genotype test again and it turned out as AS.

Please how do you explain this family people and doctors in the house? What do you do to those that conducted the 7 previous tests both in government and private hospitals?

Winneygirl:
As she is not the one making the post, there must be something we don't know yet.

Most people don't do genotype testing 7 times.
If you're AA, you do maybe one confirmatory test before marriage, that's all.

Why was she running up and down doing genotype test?
It is because she knew she was AS long ago.

chris51:



I have same opinion with you.

pragmatistm:


I tell you, she is a very upright person but the fault is with the inexperienced personnels in the various labs.

I need the medical persons to come and say something on this matter. I have just learned that to detect certain AS genotype used to be problematic in the laboratories. Please medical people, over to you.

pragmatistm:
She felt she might not be AA because she does not often fall sick like it used to happen to most AAs. That's why she did it repeatedly before marriage.

shaibu123:
Don't come to Nairaland looking for solution. Show love to your Child and take good care of your family.
It's not the end of the world.
The only solution is love ❤️

Winneygirl:
As she is not the one making the post, there must be something we don't know yet.

Most people don't do genotype testing 7 times.
If you're AA, you do maybe one confirmatory test before marriage, that's all.

Why was she running up and down doing genotype test?
It is because she knew she was AS long ago.

Ahmeduana:

Probably she played away match with an AS carrier!

Ishilove:

The woman has not yet told us how that child turned out to be SS. I put it to you that she was always AS and she knew, but maybe desperation pushed her into lying to her husband about her genotype. How can she consistently do tests over a number of years and the result is always AA, but this one time when the child is confirmed to have sickle cell anemia, she does another test and voila, she is AS. Just one time.

She is a liar and a very terrible person. Now she has brought an innocent child to suffer

NoToPile:


Not necessarily @ bolded she was most likely trying to be very sure she was AA ( Knowing how often these mistakes happen ) because she knows her fiancee is AS to avoid stuffs like this.


Its simple if you want to marry an AS, its common sense to confirm, confirm and reconfirm your AA status.

Ishilove:

The woman has not yet told us how that child turned out to be SS. I put it to you that she was always AS and she knew, but maybe desperation pushed her into lying to her husband about her genotype. How can she consistently do tests over a number of years and the result is always AA, but this one time when the child is confirmed to have sickle cell anemia, she does another test and voila, she is AS. Just one time.

She is a liar and a very terrible person. Now she has brought an innocent child to suffer

Winneygirl:
As she is not the one making the post, there must be something we don't know yet.

Most people don't do genotype testing 7 times.
If you're AA, you do maybe one confirmatory test before marriage, that's all.

Why was she running up and down doing genotype test?
It is because she knew she was AS long ago.

Verysmart101:


So all the 7 hospitals are amateurs right? I thought u were grown up honestly but am highly disappointed at ur mental stagnation honestly.