After two African villages started using mosquito nets to fight malaria, the local mosquitoes seemed to change their biting habits to avoid the barriers, according to a French study. Insecticide-treated bed nets are considered a key weapon in the global fight against malaria, which is transmitted by parasite-carrying mosquitoes and kills more than 650,000 people a year, according to the World Health Organization. In the study, which appeared in the Journal of Infectious Diseases, French researchers examined mosquito behavior before and after all households in two villages in Benin were given insecticide-treated nets. They found that mosquitoes seemed to change their hours of "peak aggression" from 2 a.m. or 3 a.m. to around 5 a.m. three years after nets were put up. And in one village, the proportion of mosquito bites inflicted outdoors rose. West Nile outbreak stresses lab testing limits, delays diagnosis Outdoor bites accounted for 45 percent of all bites at the outset but rose to 68 percent one year later and 61 percent after three years. The finding is "worrying since villagers usually wake up before dawn to work in crops, and as such they are not protected by mosquito nets," senior researcher Vincent Corbel, of the Montpellier, France-based Institute of Research for Development, said in an email. Still, the results come from just two villages in one country. "We cannot extrapolate to a wider geographical area and/or a different entomological context," Corbel warned. Malaria rates climbing again Mosquito nets have been credited with spurring big drops in malaria deaths, and a report for the Cochrane Collaboration, an international group that publishes rigorous reviews, estimated that for every 1,000 children protected by an insecticide-treated net, five to six lives would be saved every year. But in recent years, malaria cases have started to climb again in certain African countries, Corbel said. Experts have mainly been concerned about mosquitoes' growing resistance to the insecticides used in bed nets and for indoor spraying

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