Nathan Matthews, the stepbrother of missing 16-year-old Becky Watts, has been charged with her murder, Avon and Somerset Police have said.
His girlfriend, Shauna Hoare, 21, also known as Shauna Phillips, has been charged with attempting to pervert the course of justice.
The pair, of Cotton Mill Lane, Bristol, are due before magistrates on Thursday.
Four other men and a woman, all in their 20s, are still being questioned on suspicion of assisting an offender.
Mr Matthews and Ms Hoare are due to appear at Bristol Magistrates Court at 10:00 GMT on Thursday.
Ms Hoare was last night taken to hospital by officers after "feeling unwell" in custody but returned after being seen by a read more here http://24revistas..com/2015/03/stepbrother-charged-with-becky-watts.html