Though nail changes accompany many conditions, these changes are rarely the first sign. And many nail abnormalities are harmless -- not everyone with white nails has hepatitis. If you're concerned about the appearance of your nails, see a dermatologist.

But here are 14 signs you shouldn't miss

1. Yellow Nails

Your nails may yellow with age or due to the use of acrylic nails or nail polish. Smoking can also stain nails a yellowish hue. If your nails are thick, crumbly, and yellow, a fungal infection could be to blame.
Less often, yellow nails may be related to thyroid disease, diabetes, psoriasis, or respiratory disease (such as chronic bronchitis).

2. Dry, Cracked or Brittle Nails

Lifestyle factors may play a role here, such as if you have your hands in water a lot (washing dishes, swimming, etc.), use nail polish remover frequently, are exposed to chemicals (such as cleaning products) often, or live in a region with low humidity.

Cracking and splitting can also be caused by a fungal infection or thyroid disease, particularly hypothyroidism. Brittle nails may also be due to a deficiency in vitamins A and C or the B vitamin biotin.

3. Clubbing

Clubbing describes when your fingertips become enlarged and the nail becomes curved downward. It can be a sign of low oxygen in your blood and is associated with lung disease. Clubbing can also be related to liver or kidney disease, heart disease, inflammatory bowel disease, and AIDS.

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1. Yellow Nails Your nails may yellow with age or due to the use of acrylic nails or nail polish. Smoking can also stain nails a yellowish hue. If your nails are thick, crumbly, and yellow, a fungal infection could be to blame. Less often, yellow nails may be related to thyroid disease, diabetes, psoriasis, or respiratory disease (such as chronic bronchitis). 2. Dry, Cracked or Brittle Nails Lifestyle factors may play a role here, such as if you have your hands in water a lot (washing dishes, swimming, etc.), use nail polish remover frequently, are exposed to chemicals (such as cleaning products) often, or live in a region with low humidity. Cracking and splitting can also be caused by a fungal infection or thyroid disease, particularly hypothyroidism. Brittle nails may also be due to a deficiency in vitamins A and C or the B vitamin biotin. 3. Clubbing Clubbing describes when your fingertips become enlarged and the nail becomes curved downward. It can be a sign of low oxygen in your blood and is associated with lung disease. Clubbing can also be related to liver or kidney disease, heart disease, inflammatory bowel disease, and AIDS. 4. White Spots Small white spots on your nails are usually the result of nail trauma. They're not cause for concern and will fade or grow out on their own. Less commonly, white spots that do not go away could be due to a fungal infection. 5. Horizontal Ridges Horizontal ridges may also be due to trauma or a serious illness with a high fever (such as from scarlet fever or pneumonia). John Anthony, M.D., a dermatologist at the Cleveland Clinic in Ohio, explained them this way to TIME: "This is typically the result of direct trauma to the nail or a more serious illness, in which case you'll see it on more than one nail at a time … Your body is literally saying, 'I've got better things to do than make nails' and pauses their growth." Horizontal ridges, also known as Beau's lines, may also be due to psoriasis, uncontrolled diabetes, circulatory disease, or severe zinc deficiency. Another type of horizontal line is known as Mees' lines, which are horizontal discolorations that may be due to arsenic poisoning, Hodgkin's disease, malaria, leprosy, or carbon monoxide poisoning. 6. Vertical Ridges Vertical ridges are typically a normal sign of aging and are not a cause for concern. They may become more prominent as you get older. In some cases, nail ridges may be de to nutrient deficiencies, including vitamin B12 and magnesium. 7. Spoon Nails Nails that curve upward at the edges, taking on a spoon-like appearance, may be a sign of iron- deficiency anemia, hemochromatosis (excess iron absorption), heart disease, or hypothyroidism. 8. Pitting If your nails have multiple pits or dents, it's often a sign of psoriasis. Nail pitting may also be due to connective tissue disorders (including Reiter's syndrome) or alopecia areata, an autoimmune disease that causes hair loss. 9. Dark Discolorations Black streaks or painful growths on your nail warrant an immediate trip to your physician, as they may be due to melanoma, the deadliest form of skin cancer. 10. White Nails with a Strip of Pink If your nails are mostly white with a narrow pink strip at the top, known as Terry's nails, it could be a sign of liver disease, congestive heart failure, kidney failure, or diabetes. Sometimes Terry's nails may also be due to aging. 11. Gnawed Nails Biting your nails may be nothing more than an old habit, but in some cases it's a sign of persistent anxiety that could benefit from treatment. Nail biting or picking has also been linked to obsessive- compulsive disorder. If you can't stop, it's worth discussing with your doctor. 12. Puffy Nail Fold If the skin around the nail appears red and puffy, this is known as inflammation of the nail fold. It may be the result of lupus or another connective tissue disorder. Infection can also cause redness and inflammation of the nail fold. 13. Bluish Nails Nails with a bluish tint can mean the body isn't getting enough oxygen. This could indicate a lung problem, such as emphysema. Some heart problems can be associated with bluish nails. 14. Pale Nails Very pale nails can sometimes be a sign of serious illness, such as: Anemia, Congestive heart failure, Liver disease, Malnutrition Did You Like What You Read, Just type in Your Email Address, We Will Send You More Subscribe Related Posts:

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