When in-vitro fertilisation (IVF) began in 1978, some scientists were worried that the babies born as a result of it might suffer birth defects and health problems.

Intensive research in the early years, and a thriving population that has now grown to more than 5 million IVF children worldwide


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A study at the University of California appears to show that children born by IVF are more likely to be diagnosed with autism, childhood cancers and cerebral palsy. The researchers used more than 19,000 medical records to compare the pregnancies, births and child health outcomes of fertile women with those of women who conceived after fertility treatment and those who conceived naturally after a long period of infertility.

Source.

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Conflicting Research?

The study (researchers used 300, 000 as case study in Australia) found that the risk of birth defects for simple IVF is the same as the risk for babies conceived naturally. So there's no danger in just holding a little sperm and egg party in a lab. However, when ICSI is used, about 10 percent of the babies conceived using IVF had birth defects compared with only six percent of the babies conceived naturally. In terms of how birth defect is defined in this case, we're talking serious problems:

It is important to know that there are two kinds of IVF. One involves simply commingling eggs and sperm in dish and waiting for them to fertilize each other—hence the term "test tube baby." The other kind, called intracytoplasmic sperm injection (say that three times fast), is a bit more complex. ICSI involves taking single sperm and injecting it right into an egg. It was originally developed for cases where male infertility (aka faulty sperm) played a role, but it is now commonly used simply to up the odds that at least some embryos will be created—and a lot of fertility clinics do it in all cases

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Source. Jezebel.com

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Recent experiments have shown that female mice born through one sperm being injected into an egg – a process called intracytoplasmic sperm injection or ICSI – develop metabolic syndrome as they age, a combination of diabetes and obesity. Male mice were found problems with hormone function.

A study last year by the Swiss Cardiovascular Centre in Bern also found that assisted reductive children had poorer cardiovascular health.

More than 100 children were taken walking in the high altitude of the Swiss Alps, and those who had been born through IVF struggled more than natural born children, a sign that they will have poorer heart health as they age.

Telegraph

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One of (the) biggest concerns was the way IVF embryos were bathed in a cocktail of chemicals for up to five days during the phase when genetic “imprinting” is taking place.

This is a process that switches on some genes, and switches off others, and it has effects that can be passed down generations.

He added: “It could also be introducing some very interesting costs if metabolic syndrome would be one of the potential consequences of starting an embryo out in ‘rocket fuel’, some minestrone mixture that lab people have developed.”

Mirror

Wow...very interesting.

This is good information