How is your body affected by Hepatitis B virus?
According to http://kedihealthnigeria..com

Hepatitis B is an infection of your liver. It can cause scarring of the organ, liver failure, and cancer. It can be fatal if it isn’t treated.

It’s spread when people come in contact with the blood, open sores, or body fluids of someone who has the hep B virus.

The good news is that most cases of the disease don’t last a long time. Your body fights it off within a few months, and you’re immune for the rest of your life. That means you can’t get it again.
What Happens to People Who Have It?

Your doctor will know you’ve recovered when your blood tests show no signs of active infection.

But some people don’t get rid of the infection. If you have it for more than 6 months, you’re what’s called a carrier, even if you don’t have symptoms. This means you can give the disease to someone else through:

Learn what could be causing your symptoms, and what to do next.

Unprotected sex
Contact with your blood or an open sore
Sharing needles or syringes

Doctors don’t know why, but the disease does goes away in a small number of carriers. For others, it becomes what’s known as chronic. That means you have an ongoing liver infection. It can lead to cirrhosis or hardening of the organ. It scars over and stops working. Some people also get liver cancer.

If you’re a carrier or are currently infected with hepatitis B, don’t donate blood, plasma, body organs, tissue, or sperm. Tell anyone you could infect, whether it’s a sex partner, or your doctor or dentist, that you have it.

A unique characteristic of hepatitis B is that the virus itself doesn’t damage the liver cells. The body’s immune system is actually responsible for attacking the host cells . Immune response varies from person to person, causing a variety of reactions to the infection . Some people, infected with the virus, do not exhibit any signs or symptoms of the infection and simply act as carriers . Their immune system doesn’t respond to the virus and therefore, while they carry the virus, they are unaffected. There are four steps that outline the way our bodies deal with the hepatitis B virus. In the first step, the body has just been infected, and the virus spreads to the liver where it infects liver cells and begins to replicate . During this time, there are no symptoms, because the immune response has not yet kicked in . If a blood test was given at this time, markers HBsAg, HBeAg, and anti-HBc would be detected . The second step begins when the immune system detects the viral proteins on the surface of the liver cells as foreign . At this point, the immune system would begin to attack these cells and hepatitis B symptoms would begin . In addition to the blood results of step 1, transaminase levels would also be increased . In step three, the immune system attacks all the infected cells and viral replication stops. Hepatitis has now ceased, and anti-HBe appears . The other markers, viral DNA, and increased transaminase levels are no longer detected. HBsAg, however, can be detected for several months to years after infection, because the liver is capable of producing the coat protein in absence of the actual virus . The patient no longer exhibits signs or symptoms. Next, HBsAg if no longer detectable, and anti-HBs is now present. This antibody protects the patient from any future infection from hepatitis B . The complete steps of viral interaction can last weeks, in the case of an acute infection, or many years, in the case of a chronic infection. The longevity of the disease depends on the person’s immune response to the virus . Hepatitis B is classified as chronic if the HBsAg marker remains in the blood for more than six months . The key virulence factor in hepatitis B is that “HBV can hide the surface antigen from the immune system, thereby maintaining chronic infection” . “90% of healthy adults who are infected with hepatitis B virus will recover and develop protective antibodies against future hepatitis B infections”. 90% of infants, however, and 50% of young children, will develop a chronic case of hepatitis B .


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