Fibrodysplasia ossificans progressiva (FOP): A rare disease but dramatic genetic disorder that turns muscles, tendons and ligaments into bone. Fibrodysplasia ossificans progressiva (FOP) is a condition in which bone grows outside the skeleton. Abnormal bone growth replaces connective tissue, including tendons and ligaments.

FOP is caused by a genetic mutation. It’s the only recognized condition that causes one organ system to morph into another.
The average age at the onset of misplaced bone formation is 5 years (range: from birth to 25 years). The most common starting sites are the neck, spine, and shoulder girdle. Some restriction of movement is present in most (80%) cases by age 7 years. By the age of 15 years, more than 95% of the patients have severely restricted the mobility of the arms.

Although progressive, FOP is not cancerous.

Read more: https://www.healthsoothe.com/common-aftermaths-that-one-must-know-about-fibrodysplasia/
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