[Genesis 3:15]

And I will put enmity between you and the woman, And between your seed and her Seed; He shall bruise your head, and you shall bruise His heel.” [NKJV]

And I will put enmity between you and the woman, and between your seed and her seed. He will crush your head, and you will strike His heel. ” [BSB]

Though the Serpent was foremostly cursed, the Serpent was still dangerous and a potent threat because of this enmity God promised or implemented between the Serpent and the Woman.

*1* The Curse was potent: it paralyzed and reduced the Serpent. Nevertheless the Curse did not touch the Serpent's head except that Serpent shall eat dust. This made the Serpent sleek but dangerous seeing the curse only arrested the belly of the Serpent and what goes into his belly, but left out the Serpent's head, tails and offspring (seed) of the Serpent.

*2* The Enmity was added here: to arrest and end remaining threats and potencies the Serpent still had to cause problems and damages to the glorious creatures of God, particularly mankind.

In this top Bible verse above, God promised "Retribution" in the name of "Enmity" between the two parties, the Serpent and the Woman, which extended to their offsprings (seeds). Instead of God to use the Curse only to fulfill the payback or retribution, God rather reserved some rights and privileges for the Woman and her Seed to use their own hands or will to decide what happens to the Serpent and his seed. But the Serpent too was given the privilege to also bite or inflict damages to the Woman's Seed. For though the curse made the Serpent eat dust, it did not remove the ability to bite, crush, sting, venomize, or inflict wounds with his mouth. Therefore the Serpent that shall eat dust shall also have "teeth" or "power" to bite.

Thus, the vengeance or retribution was awarded to both parties, and it appeared to be in favor of the Serpent here because there was no Seed of the fallen Woman that could have stood up and defeated or harm the Serpent's head in any battle or contest between mankind and the Serpent's head that later became 7 heads when the Serpent was seen as the great Red Dragon in "Revelation 12." But the Word or Promise of God cannot fail, though mankind have fallen or failed. By implication, the way for the Seed of the Woman to be able to both endure the deadly Serpent's bite on His Heel and still be able to crush the Serpent's head in a battle or fight, without the interference of God or Angel, was by God raising the grace and abilities in the fallen Seed of the Woman to degrees far greater than the Serpent previously knew and had. Thus, God just got the Serpent curious to know who or which of the Woman's Seed will have such grace and power to withstand and crush the Serpent's head. But God kept the mystery of the Woman's Seed either foolish or confusing to the Serpent.

For that part of the prophecy or promise of God to be fulfilled, it means the Woman's Seed must have these four:

*4 — The Woman's Seed must come, though she be a Virgin: This means He must be the Seed of the Woman without the Man: Seed of a Virgin. This was done in the Virgin Birth of the Lord Jesus Christ.

*3 — The Woman's Seed must both inherit and sustain the enmity of the Woman which God implemented between the Woman and the Serpent: This means He must make neither friendship nor affinity with the Serpent the devil; not even being unequivocally yoked together with the enemy just as true light has no fellowship with darkness.

[James 4:4‭-‬7 NKJV] — Adulterers and adulteresses! Do you not know that friendship with the world is enmity with God? Whoever therefore wants to be a friend of the world makes himself an enemy of God. Or do you think that the Scripture says in vain, “The Spirit who dwells in us yearns jealously”? But He gives more grace. Therefore He says: “God resists the proud, But gives grace to the humble.” Therefore submit to God. Resist the devil and he will flee from you.

[Matthew 16:23 NKJV] — But He turned and said to Peter, “Get behind Me, Satan! You are an offense to Me, for you are not mindful of the things of God, but the things of men.”

*2 — The Woman's Seed must survive the Serpent's Bite or the Serpent's greatest chances of Retribution or Enmity. This means He must survive the Devil's Stealing, Killing and Death or Destruction thrown at that Seed of the Woman. This was done by and in the Resurrection of the Lord Jesus Christ.

*1 — The Woman's Seed must be both worthy and able to bruise or crush the Serpent's Head, even without interference of God.

So which of the Seed of the Woman met all those criteria for guaranteeimg the "Gospel of Enmity" between the Woman and the Serpent? For though God made this gospel as promise to the Serpent in awarding retribution, it was the first Gospel of redemption for mankind.