The parasites in mosquitos that spread malaria belong to the Plasmodium genus. Over 100 types of Plasmodium parasite can infect a variety of species. Different types replicate at different rates, changing how quickly the symptoms escalate, and the severity of the disease.

Five types of Plasmodium parasite can infect humans. These occur in different parts of the world. Some cause a more severe type of malaria than others.

Once an infected mosquito bites a human, the parasites multiply in the host's liver before infecting and destroying red blood cells.

In some places, early diagnosis can help treat and control malaria. However, some countries lack the resources to carry out effective screening.

A doctor would give this diagnosis when symptoms are present, but no symptoms occur that suggest severe infection or dysfunction of the vital organs.

This form can become severe malaria without treatment, or if the host has poor or no immunity.

Symptoms of uncomplicated malaria typically last 6 to 10 hours and recur every second day.

Some strains of the parasite can have a longer cycle or cause mixed symptoms.

As symptoms resemble those of flu, they may remain undiagnosed or misdiagnosed in areas where malaria is less common.

In uncomplicated malaria, symptoms progress as follows, through cold, hot, and sweating stages:

a sensation of cold with shivering
fever, headaches, and vomiting
seizures sometimes occur in younger people with the disease
sweats, followed by a return to normal temperature, with tiredness
In areas where malaria is common, many people recognize the symptoms as malaria and treat themselves without visiting a doctor.

Severe malaria
In severe malaria, clinical or laboratory evidence shows signs of vital organ dysfunction.

Symptoms of severe malaria include:

fever and chills
impaired consciousness
prostration, or adopting a prone position
multiple convulsions
deep breathing and respiratory distress
abnormal bleeding and signs of anemia
clinical jaundice and evidence of vital organ dysfunction
Severe malaria can be fatal without treatment.

PREVENTION
The Centers for Disease Control advise travelers to take the following precautions:

find out what the risk of malaria is in the country and city or region they are visiting
obtain SUPPLIMENTS FOR antimalarial before leaving home, to avoid the risk of buying counterfeit drugs while abroad
consider the risk for individual travelers, including children, older people, pregnant women, and the existing medical conditions of any travelers
Travelers to places where malaria is prevalent should take precautions, for example, using mosquito nets.
Travelers to places where malaria is prevalent should take precautions, for example, using mosquito nets.
ensure they will have access to preventative tools, many of which are available to purchase online, including insect repellants, insecticides, pre-treated bed nets, and appropriate clothing
be aware of the symptoms of malaria
In emergency situations, local health authorities in some countries may carry out "fogging," or spraying areas with pesticides similar to those used in household sprays.

The WHO points out that these are not harmful for people, as the concentration of pesticide is only strong enough to kills mosquitoes.

While away, travelers should, where possible, avoid situations that increase the risk of being bitten by mosquitoes. Precautions include taking an air-conditioned room, not camping by stagnant water, and wearing clothes that cover the body at times when mosquitoes are most likely to be around.

For a year after returning home, the traveler may be susceptible to symptoms of malaria. Donating blood may also not be possible for some time.


Causes
Malaria happens when a bite from the female Anopheles mosquito infects the body with Plasmodium. Only the Anopheles mosquito can transmit malaria.

The successful development of the parasite within the mosquito depends on several factors, the most important being humidity and ambient temperatures.

When an infected mosquito bites a human host, the parasite enters the bloodstream and lays dormant within the liver.

The host will have no symptoms for an average of 10.5 days, but the malaria parasite will begin multiplying during this time.

The liver then releases these new malaria parasites back into the bloodstream, where they infect red blood cells and multiply further. Some malaria parasites remain in the liver and do not circulate til later, resulting in recurrence.

An unaffected mosquito acquires parasites once it feeds on a human with malaria. This restarts the cycle.

Diagnosis
Early diagnosis is critical for recovery from malaria.

Anyone showing signs of malaria should seek testing and treatment immediately.

The WHO strongly advise confirmation of the parasite through microscopic laboratory testing or by a rapid diagnostic test (RDT), depending on the facilities available.

No combination of symptoms can reliably distinguish malaria from other causes, so a parasitological test is vital for identifying and managing the disease.

In some malaria-endemic areas, such as sub-Saharan Africa, the disease's severity can cause mild immunity in a large proportion of the local population.

As a result, some people carry the parasites in their bloodstream but do not fall ill.

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What Is Stomach ulcer?
Stomach ulcers are painful sores that can be found in the stomach lining or small intestine, it is one of peptic ulcer.
They occur when the thick layer of mucus that protects your stomach from digestive juices is reduced, thus enabling the digestive acids to eat away at the lining tissues of the stomach.
A stomach or gastric ulcer is a break in the tissue lining the stomach. It is usually caused by an infection with a germ (bacterium) called Helicobacter pylori (H. pylori).
A stomach ulcer is also known as gastric ulcer. The most common type of peptic ulcer is a duodenal ulcer.

Note:
Stomach ulcers are easily cured, but they can become severe without proper treatment.

When to seek medical advice


Seek urgent medical advice if you experience any of the following symptoms:

vomiting blood – the blood can appear bright red or have a dark brown, grainy appearance, similar to coffee grounds
passing dark, sticky, tar-like stools
a sudden, sharp pain in your tummy that gets steadily worse
These could be a sign of a serious complication, such as internal bleeding.

Causes of Stomach ulcer
The decrease in the stomach's mucus lining that leads to an ulcer is usually caused by one of the following:
An infection with the bacterium Helicobacter pylori (H. pylori)

Long-term use of nonsteroidal anti-inflammatory drugs, such as aspirin and ibuprofen.

Many people take NSAIDs without having any side effects, but there's always a risk the medication could cause problems, such as stomach ulcers, particularly if taken for a long time or at high doses.

Cancer: stomach cancer can present as an ulcer, particularly in older people.

Causes by Lifestyle factors

It used to be thought that stomach ulcers may be caused by certain lifestyle factors, such as
Not eating food on time (Eating Late)

Too much of spicy foods

Stress

Drink too much of alcohol

There is little hard evidence to confirm that this is the case, but these factors may make the symptoms of ulcers worse.

However, it is thought that smoking increases your risk of developing stomach ulcers and may make treatment less effective.

Symptoms/Signs of Stomach ulcer
Burning pain is the most common peptic ulcer symptom. The pain is caused by the ulcer and is aggravated by stomach acid coming in contact with the ulcerated area. There are other signs which include:
Abdominal pain just below the ribcage
Bloating
Bright or altered blood present in vomit or bowel motions
Burping or acid reflux
Dark blood in stools or stools that are black or tarry
Heartburn (burning sensation in the chest)
Indigestion
Nausea
Loss of appetite
Symptoms of anemia, such as light-headedness
The vomiting of blood — which may appear red or black
Shock due to blood loss which require medical attention (medical emergency).
Weight loss

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Infertility is defined as trying to get pregnant (with frequent intercourse) for at least a year with no success. Female infertility, male infertility or a combination of the two affects millions of couples in Nigeria. An estimated 10 to 18 percent of couples have trouble getting pregnant or having a successful delivery.

Infertility results from female factors about one-third of the time and male factors about one-third of the time. The cause is either unknown or a combination of male and female factors in the remaining cases.

Female infertility causes can be difficult to diagnose. There are many available treatments, which will depend on the cause of infertility. Many infertile couples will go on to conceive a child without treatment. After trying to get pregnant for two years, about 95 percent of couples successfully conceive.

Symptoms
The main symptom of infertility is the inability to get pregnant. A menstrual cycle that's too long (35 days or more), too short (less than 21 days), irregular or absent can mean that you're not ovulating. There may be no other outward signs or symptoms.

When to see a doctor
When to seek help sometimes depends on your age:

Up to age 35, most doctors recommend trying to get pregnant for at least a year before testing or treatment.
If you're between 35 and 40, discuss your concerns with your doctor after six months of trying.
If you're older than 40, your doctor may want to begin testing or treatment right away.
Your doctor may also want to begin testing or treatment right away if you or your partner has known fertility problems, or if you have a history of irregular or painful periods, pelvic inflammatory disease, repeated miscarriages, prior cancer treatment, or endometriosis.

Infertility is defined as trying to get pregnant (with frequent intercourse) for at least a year with no success. Female infertility, male infertility or a combination of the two affects millions of couples in the United States. An estimated 10 to 18 percent of couples have trouble getting pregnant or having a successful delivery.

Infertility results from female factors about one-third of the time and male factors about one-third of the time. The cause is either unknown or a combination of male and female factors in the remaining cases.

Female infertility causes can be difficult to diagnose. There are many available treatments, which will depend on the cause of infertility. Many infertile couples will go on to conceive a child without treatment. After trying to get pregnant for two years, about 95 percent of couples successfully conceive.

Symptoms
The main symptom of infertility is the inability to get pregnant. A menstrual cycle that's too long (35 days or more), too short (less than 21 days), irregular or absent can mean that you're not ovulating. There may be no other outward signs or symptoms.

When to see a doctor
When to seek help sometimes depends on your age:

Up to age 35, most doctors recommend trying to get pregnant for at least a year before testing or treatment.
If you're between 35 and 40, discuss your concerns with your doctor after six months of trying.
If you're older than 40, your doctor may want to begin testing or treatment right away.
Your doctor may also want to begin testing or treatment right away if you or your partner has known fertility problems, or if you have a history of irregular or painful periods, pelvic inflammatory disease, repeated miscarriages, prior cancer treatment, or endometriosis.

Each of these factors is essential to become pregnant:

You need to ovulate. To get pregnant, your ovaries must produce and release an egg, a process known as ovulation. Your doctor can help evaluate your menstrual cycles and confirm ovulation.
Your partner needs sperm. For most couples, this isn't a problem unless your partner has a history of illness or surgery. Your doctor can run some simple tests to evaluate the health of your partner's sperm.
You need to have regular intercourse. You need to have regular sexual intercourse during your fertile time. Your doctor can help you better understand when you're most fertile.
You need to have open fallopian tubes and a normal uterus. The egg and sperm meet in the fallopian tubes, and the embryo needs a healthy uterus in which to grow.
For pregnancy to occur, every step of the human reproduction process has to happen correctly. The steps in this process are:

One of the two ovaries releases a mature egg.
The egg is picked up by the fallopian tube.
Sperm swim up the cervix, through the uterus and into the fallopian tube to reach the egg for fertilization.
The fertilized egg travels down the fallopian tube to the uterus.
The fertilized egg implants and grows in the uterus.
In women, a number of factors can disrupt this process at any step. Female infertility is caused by one or more of the factors below.




Polycystic ovary syndrome (PCOS). PCOS causes a hormone imbalance, which affects ovulation. PCOS is associated with insulin resistance and obesity, abnormal hair growth on the face or body, and acne. It's the most common cause of female infertility.
Hypothalamic dysfunction. Two hormones produced by the pituitary gland are responsible for stimulating ovulation each month — (FSH) and luteinizing hormone (LH). Excess physical or emotional stress, a very high or very low body weight, or a recent substantial weight gain or loss can disrupt production of these hormones and affect ovulation. Irregular or absent periods are the most common signs.
Premature ovarian failure. Also called primary ovarian insufficiency, this disorder is usually caused by an autoimmune response or by premature loss of eggs from your ovary (possibly from genetics or chemotherapy). The ovary no longer produces eggs, and it lowers estrogen production in women under the age of 40.
Too much prolactin. The pituitary gland may cause excess production of prolactin (hyperprolactinemia), which reduces estrogen production and may cause infertility. Usually related to a pituitary gland problem, this can also be caused by medications you're taking for another disease.
Damage to fallopian tubes (tubal infertility)
Damaged or blocked fallopian tubes keep sperm from getting to the egg or block the passage of the fertilized egg into the uterus. Causes of fallopian tube damage or blockage can include:

Pelvic inflammatory disease, an infection of the uterus and fallopian tubes due to chlamydia, gonorrhea or other sexually transmitted infections
Previous surgery in the abdomen or pelvis, including surgery for ectopic pregnancy, in which a fertilized egg implants and develops in a fallopian tube instead of the uterus
Pelvic tuberculosis, a major cause of tubal infertility worldwide, although uncommon in the United States
Endometriosis
Endometriosis occurs when tissue that normally grows in the uterus implants and grows in other locations. This extra tissue growth — and the surgical removal of it — can cause scarring, which may block fallopian tubes and keep an egg and sperm from uniting.

Endometriosis can also affect the lining of the uterus, disrupting implantation of the fertilized egg. The condition also seems to affect fertility in less-direct ways, such as damage to the sperm or egg.

Uterine or cervical causes
Several uterine or cervical causes can impact fertility by interfering with implantation or increasing the likelihood of a miscarriage:

Benign polyps or tumors (fibroids or myomas) are common in the uterus. Some can block fallopian tubes or interfere with implantation, affecting fertility. However, many women who have fibroids or polyps do become pregnant.
Endometriosis scarring or inflammation within the uterus can disrupt implantation.
Uterine abnormalities present from birth, such as an abnormally shaped uterus, can cause problems becoming or remaining pregnant.
Cervical stenosis, a narrowing of the cervix, can be caused by an inherited malformation or damage to the cervix.
Sometimes the cervix can't produce the best type of mucus to allow the sperm to travel through the cervix into the uterus.
Unexplained infertility
Sometimes, the cause of infertility is never found. A combination of several minor factors in both partners could cause unexplained fertility problems. Although it's frustrating to get no specific answer, this problem may correct itself with time. But, you shouldn't delay treatment for infertility.

Risk factors
Certain factors may put you at higher risk of infertility, including:

Age. The quality and quantity of a woman's eggs begin to decline with increasing age. In the mid-30s, the rate of follicle loss speeds, resulting in fewer and poorer quality eggs. This makes conception more difficult, and increases the risk of miscarriage.

Smoking. Besides damaging your cervix and fallopian tubes, smoking increases your risk of miscarriage and ectopic pregnancy. It's also thought to age your ovaries and deplete your eggs prematurely. Stop smoking before beginning fertility treatment.

Weight. Being overweight or significantly underweight may affect normal ovulation. Getting to a healthy body mass index (BMI) may increase the frequency of ovulation and likelihood of pregnancy.

Sexual history. Sexually transmitted infections such as chlamydia and gonorrhea can damage the fallopian tubes. Having unprotected intercourse with multiple partners increases your risk of a sexually transmitted infection that may cause fertility problems later.
Alcohol. Stick to moderate alcohol consumption of no more than one alcoholic drink per day.

Prevention
If you're a woman thinking about getting pregnant soon or in the future, you may improve your chances of having normal fertility if you:

Maintain a normal weight. Overweight and underweight women are at increased risk of ovulation disorders. If you need to lose weight, exercise moderately. Strenuous, intense exercise of more than five hours a week has been associated with decreased ovulation.

Quit smoking. Tobacco has multiple negative effects on fertility, not to mention your general health and the health of a fetus. If you smoke and are considering pregnancy, quit now.

Avoid alcohol. Heavy alcohol use may lead to decreased fertility. And any alcohol use can affect the health of a developing fetus. If you're planning to become pregnant, avoid alcohol, and don't drink alcohol while you're pregnant.

Reduce stress. Some studies have shown that couples experiencing psychological stress had poorer results with infertility treatment. If you can, find a way to reduce stress in your life before trying to become pregnant.

Limit caffeine. Research suggests that limiting caffeine intake to less than 200 milligrams a day shouldn't affect your ability to get pregnant. That's about one to two cups of 6 to 8 ounces of coffee per day.
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