HT

mukina2: another good save wigan keeper

zabaleta nice pass

Althought i wont be a bad idea to replace wigan with arsenal with the play going on abi?

mukina2:
i thought it was next week

mcmanaman what a chance!

McMANNAMAN ARGH

mukina2:




Yels oh

Im finding it hard to remember a year where people where so uninterested in the FA CUP

Wigan just waiting for a smash and grab no?

oh dear

Muki na onli us?

fredoooooo: Hazarad noooooo

God don catch you..

Hazard season over?

sm1 help me check 4 a frnd: 36259195FI

Them say na luck before....this one nko

well well well..

denony: Geology -

U m@d bro?

and he lies..

dosen't matter now does it? Nothing beats that feeling of crossing the line first.

mazaje:

I will let you know, if you wan attend you sef go come see am. . .

i want to be there o..

mazaje:

And I am saying that I will come with my gun, the target will stay not far away from me, say 2 meters away from me, my gun will not jam and when I shoot at the target(arm or leg) the bullet MUST penetrate. . .



Thanks so much, I will send you an email once I get to Nigeria by the end of the month, I will have some business to take care of that might take 2 weeks of my time but after 2 weeks say by 10th of june there about I will have your time and we will do this. . .Thanks once again. . .

10,000 what? Anyway maza where d tin go go down na?

Danish scientists are expecting results that will show that “finding a mass-distributable and affordable cure to HIV is possible”.
They are conducting clinical trials to test a “novel strategy” in which the HIV virus is stripped from human DNA and destroyed permanently by the immune system.
The move would represent a dramatic step forward in the attempt to find a cure for the virus, which causes Aids.
The scientists are currently conducting human trials on their treatment, in the hope of proving that it is effective. It has already been found to work in laboratory tests.
The technique involves releasing the HIV virus from “reservoirs” it forms in DNA cells, bringing it to the surface of the cells. Once it comes to the surface, the body’s natural immune system can kill the virus through being boosted by a “vaccine”.

In vitro studies — those that use human cells in a laboratory — of the new technique proved so successful that in January, the Danish Research Council awarded the team 12 million Danish kroner (£1.5 million) to pursue their findings in clinical trials with human subjects.
These are now under way, and according to Dr Søgaard, the early signs are “promising”.
Dr Ole Søgaard, a senior researcher at the Aarhus University Hospital in Denmark who is part of the research team, said: “I am almost certain that we will be successful in releasing the reservoirs of HIV.
“The challenge will be getting the patients’ immune system to recognise the virus and destroy it. This depends on the strength and sensitivity of individual immune systems.”
Fifteen patients are currently taking part in the trials, and if they are found to have successfully been cured of HIV, the “cure” will be tested on a wider scale.
Dr Søgaard stressed that a cure is not the same as a preventative vaccine, and that raising awareness of unsafe behaviour, including unprotected sex and sharing needles, remains of paramount importance in combating HIV.
With modern HIV treatment, a patient can live an almost normal life, even into old age, with limited side effects.
However, if medication is stopped, HIV reservoirs become active and start to produce more of the virus, meaning that symptoms can reappear within two weeks.
Finding a cure would free a patient from the need to take continuous HIV medication, and save health services billions of pounds.
The technique is being researched in Britain, but studies have not yet moved on to the clinical trial stage. Five universities — Oxford, Cambridge, Imperial College, London, University College, London and King’s College, London — have jointly formed the Collaborative HIV Eradication of Reservoirs UK Biomedical Research Centre group (CHERUB), which is dedicated to finding an HIV cure.
They have applied to the Medical Research Council for funding to conduct clinical trials, which will seek to combine techniques to release the reservoirs of HIV with immunotherapy to destroy the virus.
In addition, they are focusing on patients that have only recently been infected, as they believe this will improve chances of a cure. The group hopes to receive a funding decision in May.
“When the first patient is cured in this way it will be a spectacular moment,” says Dr John Frater, a clinical research fellow at the Nuffield School of Medicine, Oxford University, and a member of the CHERUB group.
“It will prove that we are heading in the right direction and demonstrate that a cure is possible. But I think it will be five years before we see a cure that can be offered on a large scale.”
The Danish team’s research is among the most advanced and fast moving in the world, as that they have streamlined the process of putting the latest basic science discoveries into clinical testing.
This means that researchers can progress more quickly to clinical trials, accelerating the process and reaching reliable results sooner than many others.
The technique uses drugs called HDAC Inhibitors, which are more commonly used in treating cancer, to drive out the HIV from a patient’s DNA. The Danish researchers are using a particularly powerful type of HDAC inhibitor called Panobinostat.
Five years ago, the general consensus was that HIV could not be cured. But then Timothy Ray Brown, an HIV sufferer — who has become known in the field as the Berlin Patient — developed leukaemia.
He had a bone marrow transplant from a donor with a rare genetic mutation that made his cells resistant to HIV. As a result, in 2007 Mr Brown became the first man to ever be fully cured of the disease.
Replicating this procedure on a mass scale is impossible. Nevertheless, the Brown case caused a sea change in research, with scientists focusing on finding a cure as well as suppressing the symptoms.
Two principal approaches are currently being pursued. The first, gene therapy, aims to make a patient’s immune system resistant to HIV. This is complex and expensive, and not easily transferrable to diverse gene pools around the world.
The second approach is the one being pursued by Dr Søgaard and his colleagues in Denmark, the CHERUB group in Britain, and by other laboratories in the United States and Europe.

www.telegraph.co.uk/health/healthnews/10022664/Scientists-on-brink-of-HIV-cure.html

andromida: What experiences did u have at a tender age that you believe may be affecting you?

Witnessing firsthand the evils and pains of relationships. Had a relationship with an older woman too..ended in pain for me.

sholay2011: I am also like you Op (though I think say your own worse pass my own o ).

So, what is the purpose of the thread sir?

Is it for us to share experiences or 'remove that shyness' through a forum like this?

Thank you.

Let me say that maybe i want to hear opinion as to the bigger picture. Is asexuality also at play? You can also sense worry on your part and that of others no? Maybe im just scared...

Hey there, This a thread for people who consider themselves as commitment shy [like myself] to talk out thier heart albiet anonymously. Anyway, Mine can be quite bad o...I have even been described as 'Emotionally Unavailable'. I try hard to grasp the magnitude and responsibilities associated with relationship. I have long term friends of both sexes sha. How does one make him/herself available emotionally? I try to be a romantic, a good guy and all. I suck at keeping up the call/text every minute thingy. Recently, its gotten so bad that a girl told me that i need to see a doctor as she can't figure out what is always on my mind and making me distance. Could be it because of my experiences at a tender age? I have to admit that sometimes im very worried where this may leave me in future...

striktlymi:

LWKMD!!! Coachee calm down o! Lol! I will update the list with kay17...difficult keeping track of Atheists you know

Where we go come put Deepsight, Chrisbenegor and the rest of veteran FC?

SMH at atheist eleven..where plaetton, Martian, thehomer etc who be nokia3310 and kmcutez? Where the non-religous 11?

striktlymi:

I don't think so! Before any thing is made there must be a design. Even language and music have their designs. I believe the ieh here is what constitute a design.

A design is not just something we can draw or see. It is also about having a plan...which can be in someone's mind when making something. Language and music follow a set pattern which is a direct result of some careful planning and thought process.

If you conceed to the almost infinite nature of musical tunes, then you will understand the complex i speak of...Ask a class of 3-4 year olds to sing or make music, can you possible explain the careful planning behind the result?

Evil Brain: Intelligent Design is just creationism couched in big grammer. The concept only came into existence when some American fanatics wanted to pretend creationism was a scientific theory so they could teach their religious nonsense in public school science classrooms.

ID is not science. It is concept that has more holes in than a laundry basket. No serious minded biologists give the idea any credit, and it can be easily disproved by simple experiments or just a few moments thought.

Dont you think that scientific methodology havent been applied to it? Or do you want to disprove it?

striktlymi: Good morning mk,

Do you think it is possible for one to 'create' without considering the design of what is to be created?

It is..Creativity complex permit creation without design complex e.g Language,Music etc

Any thoughts?

2) Difference from goals:Creationism is ultimately about the defense of a particular interpretation of religious texts, hence, why dominant scientific themes in creation science, are things like the age of the earth etc. Where as, Intelligent Design attempts to build a rigorous scientific method for detecting design, and applying this to patterns in nature.